Epicardial Adipose Tissue and Progression of Coronary Artery Calcium

Epicardial adipose tissue and progression of coronary artery calcium: cause and effect or simple association?

I n this issue of iJACC, Mahabadi et al. (1) describe a parallel increase of subclinical atherosclerosis and epicardial adipose tissue (EAT). Two prior publications (2,3) reported a similar association, and together with experimental models, they support the role of EAT in atherosclerosis inception and progression. In an experimental porcine model, the investigators stripped the epicardial fat ...

Can epicardial adipose tissue predict coronary artery plaque?

Epicardial Adipose Tissue Reflects the Presence of Coronary Artery Disease: Comparison with Abdominal Visceral Adipose Tissue

Accumulation of visceral adipose tissue is associated with a risk of coronary artery disease (CAD). The aim of this study was to examine whether different types of adipose tissue depot may play differential roles in the progression of CAD. Consecutive 174 patients who underwent both computed tomography (CT) and echocardiography were analyzed. Cardiac and abdominal CT scans were performed to mea...

Epicardial adipose excision slows the progression of porcine coronary atherosclerosis

BACKGROUND In humans there is a positive association between epicardial adipose tissue (EAT) volume and coronary atherosclerosis (CAD) burden. We tested the hypothesis that EAT contributes locally to CAD in a pig model. METHODS Ossabaw miniature swine (n=9) were fed an atherogenic diet for 6 months to produce CAD. A 15 mm length by 3-5 mm width coronary EAT (cEAT) resection was performed over...

Does epicardial adipose tissue volume provide information about the presence and localization of coronary artery disease?

OBJECTIVE This study is important for the determination of branches and segments of the first atherosclerotic coronary artery. The objective was to examine the role of epicardial adipose tissue (EAT) volume in estimating the presence and localization of plaque of coronary arteries. METHODS Our study is a retrospective study, consisting of 50 male (mean age: 45.5 ± 12 yrs) and 58 female (mean ...